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61
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Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis
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Alton, Eric W F W;
Beekman, Jeffery M;
Boyd, A Christopher;
Brand, June;
Carlon, Marianne S;
Connolly, Mary M;
Chan, Mario;
Conlon, Sinead;
Davidson, Heather E;
Davies, Jane C;
Davies, Lee A;
Dekkers, Johanna F;
Doherty, Ann;
Gea-Sorli, Sabrina;
Gill, Deborah R;
Griesenbach, Uta;
Hasegawa, Mamoru;
Higgins, Tracy E;
Hironaka, Takashi;
Hyndman, Laura;
McLachlan, Gerry;
Inoue, Makoto;
Hyde, Stephen C;
Innes, J Alastair;
Maher, Toby M;
Moran, Caroline;
Meng, Cuixiang;
Paul-Smith, Michael C;
Pringle, Ian A;
Pytel, Kamila M;
Rodriguez-Martinez, Andrea;
Schmidt, Alexander C;
Stevenson, Barbara J;
Sumner-Jones, Stephanie G;
Toshner, Richard;
Tsugumine, Shu;
Wasowicz, Marguerite W;
Zhu, Jie;
Department of Gene Therapy , National Heart and Lung Institute, Imperial College London , London , UK;
Department of Pediatric Pulmonology, Laboratory of Translational Immunology , Wilhelmina Children's Hospital, University Medical Centre , Utrecht , The Netherlands;
Centre for Genomic and Experimental Medicine, IGMM, University of Edinburgh , Edinburgh , UK;
Centre for Genomic and Experimental Medicine, IGMM, University of Edinburgh , Edinburgh , UK;
Laboratory for Molecular Virology and Gene Therapy, Department of Pharmaceutical and Pharmacological Sciences, KU Leuven , Brussels , Belgium;
UK Cystic Fibrosis Gene Therapy Consortium , Oxford , UK;
Department of Gene Therapy , National Heart and Lung Institute, Imperial College London , London , UK;
Department of Gene Therapy , National Heart and Lung I;
(Thorax,
v.72,
2017,
pp.137-147)
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62
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Clustered mutations in the GRIK2 kainate receptor subunit gene underlie diverse neurodevelopmental disorders
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Stolz, Jacob R.;
Foote, Kendall M.;
Veenstra-Knol, Hermine E.;
Pfundt, Rolph;
ten Broeke, Sanne W.;
de Leeuw, Nicole;
Roht, Laura;
Pajusalu, Sander;
Part, Reelika;
Rebane, Ionella;
Õ
unap, Katrin;
Stark, Zornitza;
Kirk, Edwin P.;
Lawson, John A.;
Lunke, Sebastian;
Christodoulou, John;
Louie, Raymond J.;
Rogers, R. Curtis;
Davis, Jessica M.;
Innes, A. Micheil;
Wei, Xing-Chang;
Keren, Boris;
Mignot, Cyril;
Lebel, Robert Roger;
Sperber, Steven M.;
Sakonju, Ai;
Dosa, Nienke;
Barge-Schaapveld, Daniela Q.C.M.;
Peeters-Scholte, Cacha M.P.C.D.;
Ruivenkamp, Claudia A.L.;
van Bon, Bregje W.;
Kennedy, Joanna;
Low, Karen J.;
Ellard, Sian;
Pang, Lewis;
Junewick, Joseph J.;
Mark, Paul R.;
Carvill, Gemma L.;
Swanson, Geoffrey T.;
;
(American journal of human genetics,
v.108,
2021,
pp.2206)
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63
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<i>Bacillus subtilis</i> YxaG is a novel Fe-containing quercetin 2,3-dioxygenase
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Bowater, Laura;
Fairhurst, Shirley A;
Just, Victoria J;
Bornemann, Stephen;
Biological Chemistry Department, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK;
Biological Chemistry Department, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK;
Biological Chemistry Department, John Innes Centre, Norwich Research Park, Colney, Norwich NR4 7UH, UK;
Corresponding author. Fax: (44)-1603-450018;
(FEBS letters,
v.557,
2004,
pp.45-48)
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64
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Anthea Innes, Fiona Kelly, and Louise McCabe, Eds. Key Issues in Evolving Dementia Care: International Theory-Based Policy and Practice. Philadelphia, PA: Jessica Kingsley Publishers, 2012.
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Booi, Laura;
;
(Canadian journal on aging = La revue canadienne du vieillissement,
v.33,
2014,
pp.100-102)
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65
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Repeated nebulisation of non-viral <i>CFTR</i> gene therapy in patients with cystic fibrosis: a randomised, double-blind, placebo-controlled, phase 2b trial
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Alton, Eric W F W;
Armstrong, David K;
Ashby, Deborah;
Bayfield, Katie J;
Bilton, Diana;
Bloomfield, Emily V;
Boyd, A Christopher;
Brand, June;
Buchan, Ruaridh;
Calcedo, Roberto;
Carvelli, Paula;
Chan, Mario;
Cheng, Seng H;
Collie, D David S;
Cunningham, Steve;
Davidson, Heather E;
Davies, Gwyneth;
Davies, Jane C;
Davies, Lee A;
Dewar, Maria H;
Doherty, Ann;
Donovan, Jackie;
Dwyer, Natalie S;
Elgmati, Hala I;
Featherstone, Rosanna F;
Gavino, Jemyr;
Gea-Sorli, Sabrina;
Geddes, Duncan M;
Gibson, James S R;
Gill, Deborah R;
Greening, Andrew P;
Griesenbach, Uta;
Hansell, David M;
Harman, Katharine;
Higgins, Tracy E;
Hodges, Samantha L;
Hyde, Stephen C;
Hyndman, Laura;
Innes, J Alastair;
Jacob, Joseph;
Jones, Nancy;
Keogh, Brian F;
Limberis, Maria P;
Lloyd-Evans, Paul;
Maclean, Alan W;
Manvell, Michelle C;
McCormick, Dominique;
McGovern, Michael;
McLachlan, Gerry;
Meng, Cuixiang;
Montero, M Angeles;
Milligan, Hazel;
Moyce, Laura J;
Murray;
Imperial College London, London, UK;
Royal Hospital for Sick Children, Edinburgh, UK;
Imperial College London, London, UK;
Imperial College London, London, UK;
Royal Brompton and Harefield NHS Foundation Trust, London, UK;
Imperial College London, London, UK;
Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK;
Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK;
Western General Hospital, Edinburgh, UK;
Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA;
Imperial College London, London, UK;
Imperial College London, London, UK;
Genzyme, a Sanofi Company, Framingham, MA, USA;
The Roslin Institute and R(D)SVS, University of Edinburgh, Edinburgh, UK;
Royal Hospital for Sick Children, Edinburgh, UK;
Centre for Genomic and Experimental Medicine, Institu;
(The Lancet. Respiratory medicine,
v.3,
2015,
pp.684-691)
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66
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A randomised, double-blind, placebo-controlled trial of repeated nebulisation of non-viral cystic fibrosis transmembrane conductance regulator (CFTR) gene therapy in patients with cystic fibrosis
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Alton, Eric WFW;
Armstrong, David K;
Ashby, Deborah;
Bayfield, Katie J;
Bilton, Diana;
Bloomfield, Emily V;
Boyd, A Christopher;
Brand, June;
Buchan, Ruaridh;
Calcedo, Roberto;
Carvelli, Paula;
Chan, Mario;
Cheng, Seng H;
Collie, David S;
Cunningham, Steve;
Davidson, Heather E;
Davies, Gwyneth;
Davies, Jane C;
Davies, Lee A;
Dewar, Maria H;
Doherty, Ann;
Donovan, Jackie;
Dwyer, Natalie S;
Elgmati, Hala I;
Featherstone, Rosanna F;
Gavino, Jemyr;
Gea-Sorli, Sabrina;
Geddes, Duncan M;
Gibson, James SR;
Gill, Deborah R;
Greening, Andrew P;
Griesenbach, Uta;
Hansell, David M;
Harman, Katharine;
Higgins, Tracy E;
Hodges, Samantha L;
Hyde, Stephen C;
Hyndman, Laura;
Innes, J Alastair;
Jacob, Joseph;
Jones, Nancy;
Keogh, Brian F;
Limberis, Maria P;
Lloyd-Evans, Paul;
Maclean, Alan W;
Manvell, Michelle C;
McCormick, Dominique;
McGovern, Michael;
McLachlan, Gerry;
Meng, Cuixiang;
Montero, M Angeles;
Milligan, Hazel;
Moyce, Laura J;
Murray, Gor;
Department of Gene Therapy, Imperial College London, London, UK;
Medical Genetics, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK;
Department of Gene Therapy, Imperial College London, London, UK;
Department of Gene Therapy, Imperial College London, London, UK;
Department of Gene Therapy, Imperial College London, London, UK;
Department of Gene Therapy, Imperial College London, London, UK;
Medical Genetics, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK;
Medical Genetics, Centre for Genomic and Experimental Medicine, University of Edinburgh, Edinburgh, UK;
Western General Hospital, Edinburgh, UK;
Gene Therapy Program, Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, USA;
Department of Gene Therapy, Imperial College London, London, UK;
Department of Gene Therapy, Imperial College London, London, UK;
Genzyme, a Sanofi Company, Framingham, MA, USA;
The Rosli;
(Efficacy and mechanism evaluation,
v.3,
2016,
pp.1-210)
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67
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The identity of the active site of oxalate decarboxylase and the importance of the stability of active-site lid conformations
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Just, Victoria J.;
Burrell, Matthew R.;
Bowater, Laura;
McRobbie, Iain;
Stevenson, Clare E. M.;
Lawson, David M.;
Bornemann, Stephen;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
Department of Biological Chemistry, John Innes Centre, Norwich Research Park, Norwich NR4 7UH, U.K.;
(The Biochemical journal,
v.407,
2007,
pp.397-406)
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68
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Multiple Candidate Effectors from the Oomycete Pathogen <i>Hyaloperonospora arabidopsidis</i> Suppress Host Plant Immunity
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Fabro, Georgina;
Steinbrenner, Jens;
Coates, Mary;
Ishaque, Naveed;
Baxter, Laura;
Studholme, David J.;
Kö
rner, Evelyn;
Allen, Rebecca L.;
Piquerez, Sophie J. M.;
Rougon-Cardoso, Alejandra;
Greenshields, David;
Lei, Rita;
Badel, Jorge L.;
Caillaud, Marie-Cecile;
Sohn, Kee-Hoon;
Van den Ackerveken, Guido;
Parker, Jane E.;
Beynon, Jim;
Jones, Jonathan D. G.;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
School of Life Sciences, Warwick University, Wellesbourne, United Kingdom;
School of Life Sciences, Warwick University, Wellesbourne, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
School of Life Sciences, Warwick University, Wellesbourne, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
School of Life Sciences, Warwick University, Wellesbourne, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, United Kingdom;
The Sainsbury Laboratory, John Innes Centre, Norwich, Uni;
(PLoS pathogens,
v.7,
2011,
pp.e1002348)
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69
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TAF1 Variants Are Associated with Dysmorphic Features, Intellectual Disability, and Neurological Manifestations
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O'Rawe, Jason A.;
Wu, Y.;
Dorfel, Max J.;
Rope, Alan F.;
Au, P.;
Parboosingh, Jillian S.;
Moon, S.;
Kousi, M.;
Kosma, K.;
Smith, Christopher S.;
Tzetis, M.;
Schuette, Jane L.;
Hufnagel, Robert B.;
Prada, Carlos E.;
Martinez, F.;
Orellana, C.;
Crain, J.;
Caro-Llopis, A.;
Oltra, S.;
Monfort, S.;
Jimenez-Barron, Laura T.;
Swensen, J.;
Ellingwood, S.;
Smith, R.;
Fang, H.;
Ospina, S.;
Stegmann, S.;
Den Hollander, N.;
Mittelman, D.;
Highnam, G.;
Robison, R.;
Yang, E.;
Faivre, L.;
Roubertie, A.;
Riviere, J.B.;
Monaghan, Kristin G.;
Wang, K.;
Davis, Erica E.;
Katsanis, N.;
Kalscheuer, Vera M.;
Wang, Edith H.;
Metcalfe, K.;
Kleefstra, T.;
Innes, A.;
Kitsiou-Tzeli, S.;
Rosello, M.;
Keegan, Catherine E.;
Lyon, Gholson J.;
;
(American journal of human genetics,
v.97,
2015,
pp.922-932)
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70
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Clustered mutations in the <i>GRIK2</i> kainate receptor subunit gene underlie diverse neurodevelopmental disorders
-
Stolz, Jacob R.;
Foote, Kendall M.;
Veenstra-Knol, Hermine E.;
Pfundt, Rolph;
ten Broeke, Sanne W.;
de Leeuw, Nicole;
Roht, Laura;
Pajusalu, Sander;
Part, Reelika;
Rebane, Ionella;
Õ
unap, Katrin;
Stark, Zornitza;
Kirk, Edwin P.;
Lawson, John A.;
Lunke, Sebastian;
Christodoulou, John;
Louie, Raymond J.;
Rogers, R. Curtis;
Davis, Jessica M.;
Innes, A. Micheil;
Wei, Xing-Chang;
Keren, Boris;
Mignot, Cyril;
Lebel, Robert Roger;
Sperber, Steven M.;
Sakonju, Ai;
Dosa, Nienke;
Barge-Schaapveld, Daniela Q.C.M.;
Peeters-Scholte, Cacha M.P.C.D.;
Ruivenkamp, Claudia A.L.;
van Bon, Bregje W.;
Kennedy, Joanna;
Low, Karen J.;
Ellard, Sian;
Pang, Lewis;
Junewick, Joseph J.;
Mark, Paul R.;
Carvill, Gemma L.;
Swanson, Geoffrey T.;
Department of Pharmacology, Feinberg School of Medicine, Northwestern University;
Department of Pharmacology, Feinberg School of Medicine, Northwestern University;
Department of Genetics, University Medical Center Groningen;
Department of Human Genetics, Radboud University Nijmegen Medical Centre;
Department of Genetics, University Medical Center Groningen;
Department of Human Genetics, Radboud University Nijmegen Medical Centre;
Department of Clinical Genetics, Tartu University Hospital;
Department of Clinical Genetics, Tartu University Hospital;
Department of Neonatal and Infant Medicine, Tallinn Children’s Hospital;
Department of Neonatal and Infant Medicine, Tallinn Children’s Hospital Estonia