검색어 : 통합검색[Miles Alastair.]
-
31
-
A systems genomics approach to uncover patient-specific pathogenic pathways in a complex disease
-
Brooks Johanne;
Modos Dezso;
Sudhakar Padhmanand;
Fazekas David;
Zoufir Azedine;
Kapuy Orsolya;
Szalay-Beko Mate;
Madgwick Matthew;
Verstockt Bram;
Hall Lindsay;
Watson Alastair;
Tremelling Mark;
Parkes Miles;
Vermeire Severine;
Bender Andreas;
Carding Simon R.;
Korcsmaros Tamas;
;
(,
v.,
2019,
)
-
32
-
First‐in‐man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M<sub>1</sub>‐receptor partial agonist for the treatment of dementias
-
Bakker, Charlotte;
Tasker, Tim;
Liptrot, Jan;
Hart, Ellen P.;
Klaassen, Erica S.;
Prins, Samantha;
van der Doef, Thalia F.;
Brown, Giles A.;
Brown, Alastair;
Congreve, Miles;
Weir, Malcolm;
Marshall, Fiona H.;
Cross, David M.;
Groeneveld, Geert Jan;
Nathan, Pradeep J.;
Centre for Human Drug Research (CDHR), Leiden, Netherlands;
Sosei Heptares, Cambridge, UK;
Sosei Heptares, Cambridge, UK;
Centre for Human Drug Research (CDHR), Leiden, Netherlands;
Centre for Human Drug Research (CDHR), Leiden, Netherlands;
Centre for Human Drug Research (CDHR), Leiden, Netherlands;
Centre for Human Drug Research (CDHR), Leiden, Netherlands;
OMass Therapeutics Ltd, Oxford, UK;
Sosei Heptares, Cambridge, UK;
Sosei Heptares, Cambridge, UK;
Sosei Heptares, Cambridge, UK;
Merck Sharp & Dohme Limited, London, UK xxk
-
33
-
A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis
-
Brooks-Warburton, Johanne;
Modos, Dezso;
Sudhakar, Padhmanand;
Madgwick, Matthew;
Thomas, John P.;
Bohar, Balazs;
Fazekas, David;
Zoufir, Azedine;
Kapuy, Orsolya;
Szalay-Beko, Mate;
Verstockt, Bram;
Hall, Lindsay J.;
Watson, Alastair;
Tremelling, Mark;
Parkes, Miles;
Vermeire, Severine;
Bender, Andreas;
Carding, Simon R.;
Korcsmaros, Tamas;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Earlham Institute, Norwich Research Park, Norwich, UK;
Centre for Molecular Science Informatics, Department of Chemistry, University of Cambridge, Cambridge, UK;
Department of Molecular Biology, Semmelweis University, Budapest, Hungary;
Earlham Institute, Norwich Research Park, Norwich, UK;
KU Leuven, Department of Chronic diseases, Metabolism and Ageing, Leuven, Belgium;
Gut Microbes and Health Programme, The Quadram Institute Bioscience, Norwich Research Park, Norwich, UK;
Department of Gastroenterology, Norfolk and Norwich University Hospitals, Norwich, UK;
Department of Gastroenterology, Norfolk and Norwich University Hospitals, Norwich, UK;
In;
(Nature communications,
v.13,
2022,
pp.2299)
-
34
-
The Creation
-
Rushton, Julian;
Haydn,;
Monoyios, Ann;
Hering, Jorg;
van der Kamp, Harry;
Knabenchor, Tolzer;
Tafelmusik,;
Weil, Bruno;
Vallin, Marie-Claude;
L'Archibudelli,;
Bonney, Barbara;
von Magnus, Elisabeth;
Lippert, Herbert;
Miles, Alastair;
Choir, Arnold Schoenberg;
Wien, Concentus Musicus;
Harnoncourt, Nikolaus;
Mozart,;
McNair, Sylvia;
Margiono, Charlotte;
Pregardien, Christoph;
Hampson, Thomas;
Bortnyansky,;
Chernoushenko, Vladislav;
;
(The musical times,
v.136,
1995,
pp.500)
-
35
-
Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist
-
Jazayeri, Ali;
Rappas, Mathieu;
Brown, Alastair J. H.;
Kean, James;
Errey, James C.;
Robertson, Nathan J.;
Fiez-Vandal, Cé
dric;
Andrews, Stephen P.;
Congreve, Miles;
Bortolato, Andrea;
Mason, Jonathan S.;
Baig, Asma H.;
Teobald, Iryna;
Doré
, Andrew S.;
Weir, Malcolm;
Cooke, Robert M.;
Marshall, Fiona H.;
;
(Nature,
v.548,
2017,
pp.122-122)
-
36
-
Structure-Based Drug Discovery of <i>N</i>-((<i>R</i>)-3-(7-Methyl-1<i>H</i>-indazol-5-yl)-1-oxo-1-(((<i>S</i>)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2′-oxo-1′,2′-dihydrospiro[piperidine-4,4′-pyrido[2,3-<i>d</i>][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine
-
Bucknell, Sarah J.;
Ator, Mark A.;
Brown, Alastair J. H.;
Brown, Jason;
Cansfield, Andrew D.;
Cansfield, Julie E.;
Christopher, John A.;
Congreve, Miles;
Cseke, Gabriella;
Deflorian, Francesca;
Jones, Christopher R.;
Mason, Jonathan S.;
O’Brien, M. Alistair;
Ott, Gregory R.;
Pickworth, Mark;
Southall, Stacey M.;
Teva Pharmaceuticals , 145 Brandywine Parkway , West Chester , Pennsylvania 19380 , United States;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.;
Sosei Heptares , Steinmetz;
(Journal of medicinal chemistry,
v.63,
2020,
pp.7906-7920)
-
37
-
Self-sampling to identify pathogens and inflammatory markers in patients with acute sore throat: Feasibility study
-
Lown, Mark;
Miles, Elizabeth A.;
Fisk, Helena L.;
Smith, Kirsten A.;
Muller, Ingrid;
Maund, Emma;
Rogers, Kirsty;
Becque, Taeko;
Hayward, Gail;
Moore, Michael;
Little, Paul;
Glogowska, Margaret;
Hay, Alastair D.;
Stuart, Beth;
Mantzourani, Efi;
Butler, Chris;
Bostock, Jennifer;
Davies, Firoza;
Dickerson, Ian;
Thompson, Natalie;
Francis, Nick;
Primary Care Research Centre, University of Southampton , Southampton , United Kingdom;
School of Human Development and Health, Faculty of Medicine, University of Southampton , Southampton , United Kingdom;
School of Human Development and Health, Faculty of Medicine, University of Southampton , Southampton , United Kingdom;
Primary Care Research Centre, University of Southampton , Southampton , United Kingdom;
Primary Care Research Centre, University of Southampton , Southampton , United Kingdom;
Primary Care Research Centre, University of Southampton , Southampton , United Kingdom;
Primary Care Research Centre, University of Southampton , Southampton , United Kingdom;
Primary Care Research Centre, University of Southampton , Southampton;
(Frontiers in immunology,
v.13,
2022,
pp.1016181)
-
38
-
Measurements towards providing security assurance for a chip-scale QKD system
-
Hart, Andy;
Kirkwood, Robert;
Semenenko, Henry;
Sibson, Philip;
Chunnilall, Christopher J.;
Vaquero-Stainer, Anthony;
Sinclair, Alastair G.;
Burenkov, Viacheslav;
Erven, Chris;
Thompson, Mark G.;
Shields, Andrew J.;
Stuhler, Jü
rgen;
Padgett, Miles J.;
;
(Quantum Technologies 2018,
v.2018,
2018,
pp.46)
-
39
-
Crystal structure of the GLP-1 receptor bound to a peptide agonist
-
Jazayeri, Ali;
Rappas, Mathieu;
Brown, Alastair J. H.;
Kean, James;
Errey, James C.;
Robertson, Nathan J.;
Fiez-Vandal, Cé
dric;
Andrews, Stephen P.;
Congreve, Miles;
Bortolato, Andrea;
Mason, Jonathan S.;
Baig, Asma H.;
Teobald, Iryna;
Doré
, Andrew S.;
Weir, Malcolm;
Cooke, Robert M.;
Marshall, Fiona H.;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK;
Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7;
(Nature,
v.546,
2017,
pp.254-258)
-
40
-
IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease
-
Tremelling, Mark;
Cummings, Fraser;
Fisher, Sheila A.;
Mansfield, John;
Gwilliam, Rhian;
Keniry, Andrew;
Nimmo, Elaine R.;
Drummond, Hazel;
Onnie, Clive M.;
Prescott, Natalie J.;
Sanderson, Jeremy;
Bredin, Francesca;
Berzuini, Carlo;
Forbes, Alastair;
Lewis, Cathryn M.;
Cardon, Lon;
Deloukas, Panos;
Jewell, Derek;
Mathew, Christopher G.;
Parkes, Miles;
Satsangi, Jack;
IBD Research Group, Addenbrooke’s Hospital, University of Cambridge, Cambridge, England;
Gastroenterology Unit, Radcliffe Infirmary, University of Oxford, Oxford, England;
Division of Genetics and Molecular Medicine, Guy’s, King’s College and St Thomas’ School of Medicine, London, England;
Faculty of Medical Sciences, University of Newcastle, Newcastle upon Tyne, England;
Wellcome Trust Sanger Institute, Hinxton, Cambridge, England;
Wellcome Trust Sanger Institute, Hinxton, Cambridge, England;
Department of Gastroenterology, University of Edinburgh, and Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland;
Department of Gastroenterology, University of Edinburgh, and Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland;
Department of Medical and Molecular Genetics, King’s College London School of Medicine, Guy’s Hospital, London, United Kingdom;
Department of Medical and Molecular Genetics, King’s College London School of Medicine,;
(Gastroenterology,
v.132,
2007,
pp.1657-1664)