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검색어 : 통합검색[Miles Alastair.]

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  • 31
    A systems genomics approach to uncover patient-specific pathogenic pathways in a complex disease
    Brooks Johanne; Modos Dezso; Sudhakar Padhmanand; Fazekas David; Zoufir Azedine; Kapuy Orsolya; Szalay-Beko Mate; Madgwick Matthew; Verstockt Bram; Hall Lindsay; Watson Alastair; Tremelling Mark; Parkes Miles; Vermeire Severine; Bender Andreas; Carding Simon R.; Korcsmaros Tamas; ; (, v., 2019, )
  • 32
    First&#x2010;in&#x2010;man study to investigate safety, pharmacokinetics and exploratory pharmacodynamics of HTL0018318, a novel M<sub>1</sub>&#x2010;receptor partial agonist for the treatment of dementias
    Bakker, Charlotte; Tasker, Tim; Liptrot, Jan; Hart, Ellen P.; Klaassen, Erica S.; Prins, Samantha; van der Doef, Thalia F.; Brown, Giles A.; Brown, Alastair; Congreve, Miles; Weir, Malcolm; Marshall, Fiona H.; Cross, David M.; Groeneveld, Geert Jan; Nathan, Pradeep J.; Centre for Human Drug Research (CDHR), Leiden, Netherlands; Sosei Heptares, Cambridge, UK; Sosei Heptares, Cambridge, UK; Centre for Human Drug Research (CDHR), Leiden, Netherlands; Centre for Human Drug Research (CDHR), Leiden, Netherlands; Centre for Human Drug Research (CDHR), Leiden, Netherlands; Centre for Human Drug Research (CDHR), Leiden, Netherlands; OMass Therapeutics Ltd, Oxford, UK; Sosei Heptares, Cambridge, UK; Sosei Heptares, Cambridge, UK; Sosei Heptares, Cambridge, UK; Merck Sharp & Dohme Limited, London, UK xxk
  • 33
    A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis
    Brooks-Warburton, Johanne; Modos, Dezso; Sudhakar, Padhmanand; Madgwick, Matthew; Thomas, John P.; Bohar, Balazs; Fazekas, David; Zoufir, Azedine; Kapuy, Orsolya; Szalay-Beko, Mate; Verstockt, Bram; Hall, Lindsay J.; Watson, Alastair; Tremelling, Mark; Parkes, Miles; Vermeire, Severine; Bender, Andreas; Carding, Simon R.; Korcsmaros, Tamas; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Earlham Institute, Norwich Research Park, Norwich, UK; Centre for Molecular Science Informatics, Department of Chemistry, University of Cambridge, Cambridge, UK; Department of Molecular Biology, Semmelweis University, Budapest, Hungary; Earlham Institute, Norwich Research Park, Norwich, UK; KU Leuven, Department of Chronic diseases, Metabolism and Ageing, Leuven, Belgium; Gut Microbes and Health Programme, The Quadram Institute Bioscience, Norwich Research Park, Norwich, UK; Department of Gastroenterology, Norfolk and Norwich University Hospitals, Norwich, UK; Department of Gastroenterology, Norfolk and Norwich University Hospitals, Norwich, UK; In; (Nature communications, v.13, 2022, pp.2299)
  • 34
    The Creation
    Rushton, Julian; Haydn,; Monoyios, Ann; Hering, Jorg; van der Kamp, Harry; Knabenchor, Tolzer; Tafelmusik,; Weil, Bruno; Vallin, Marie-Claude; L'Archibudelli,; Bonney, Barbara; von Magnus, Elisabeth; Lippert, Herbert; Miles, Alastair; Choir, Arnold Schoenberg; Wien, Concentus Musicus; Harnoncourt, Nikolaus; Mozart,; McNair, Sylvia; Margiono, Charlotte; Pregardien, Christoph; Hampson, Thomas; Bortnyansky,; Chernoushenko, Vladislav; ; (The musical times, v.136, 1995, pp.500)
  • 35
    Corrigendum: Crystal structure of the GLP-1 receptor bound to a peptide agonist
    Jazayeri, Ali; Rappas, Mathieu; Brown, Alastair J. H.; Kean, James; Errey, James C.; Robertson, Nathan J.; Fiez-Vandal, Cé dric; Andrews, Stephen P.; Congreve, Miles; Bortolato, Andrea; Mason, Jonathan S.; Baig, Asma H.; Teobald, Iryna; Doré , Andrew S.; Weir, Malcolm; Cooke, Robert M.; Marshall, Fiona H.; ; (Nature, v.548, 2017, pp.122-122)
  • 36
    Structure-Based Drug Discovery of <i>N</i>-((<i>R</i>)-3-(7-Methyl-1<i>H</i>-indazol-5-yl)-1-oxo-1-(((<i>S</i>)-1-oxo-3-(piperidin-4-yl)-1-(4-(pyridin-4-yl)piperazin-1-yl)propan-2-yl)amino)propan-2-yl)-2′-oxo-1′,2′-dihydrospiro[piperidine-4,4′-pyrido[2,3-<i>d</i>][1,3]oxazine]-1-carboxamide (HTL22562): A Calcitonin Gene-Related Peptide Receptor Antagonist for Acute Treatment of Migraine
    Bucknell, Sarah J.; Ator, Mark A.; Brown, Alastair J. H.; Brown, Jason; Cansfield, Andrew D.; Cansfield, Julie E.; Christopher, John A.; Congreve, Miles; Cseke, Gabriella; Deflorian, Francesca; Jones, Christopher R.; Mason, Jonathan S.; O’Brien, M. Alistair; Ott, Gregory R.; Pickworth, Mark; Southall, Stacey M.; Teva Pharmaceuticals , 145 Brandywine Parkway , West Chester , Pennsylvania 19380 , United States; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz Building, Granta Park , Great Abington, Cambridge CB21 6DG , U.K.; Sosei Heptares , Steinmetz; (Journal of medicinal chemistry, v.63, 2020, pp.7906-7920)
  • 37
    Self-sampling to identify pathogens and inflammatory markers in patients with acute sore throat: Feasibility study
    Lown, Mark; Miles, Elizabeth A.; Fisk, Helena L.; Smith, Kirsten A.; Muller, Ingrid; Maund, Emma; Rogers, Kirsty; Becque, Taeko; Hayward, Gail; Moore, Michael; Little, Paul; Glogowska, Margaret; Hay, Alastair D.; Stuart, Beth; Mantzourani, Efi; Butler, Chris; Bostock, Jennifer; Davies, Firoza; Dickerson, Ian; Thompson, Natalie; Francis, Nick; Primary Care Research Centre, University of Southampton , Southampton , United Kingdom; School of Human Development and Health, Faculty of Medicine, University of Southampton , Southampton , United Kingdom; School of Human Development and Health, Faculty of Medicine, University of Southampton , Southampton , United Kingdom; Primary Care Research Centre, University of Southampton , Southampton , United Kingdom; Primary Care Research Centre, University of Southampton , Southampton , United Kingdom; Primary Care Research Centre, University of Southampton , Southampton , United Kingdom; Primary Care Research Centre, University of Southampton , Southampton , United Kingdom; Primary Care Research Centre, University of Southampton , Southampton; (Frontiers in immunology, v.13, 2022, pp.1016181)
  • 38
    Measurements towards providing security assurance for a chip-scale QKD system
    Hart, Andy; Kirkwood, Robert; Semenenko, Henry; Sibson, Philip; Chunnilall, Christopher J.; Vaquero-Stainer, Anthony; Sinclair, Alastair G.; Burenkov, Viacheslav; Erven, Chris; Thompson, Mark G.; Shields, Andrew J.; Stuhler, Jü rgen; Padgett, Miles J.; ; (Quantum Technologies 2018, v.2018, 2018, pp.46)
  • 39
    Crystal structure of the GLP-1 receptor bound to a peptide agonist
    Jazayeri, Ali; Rappas, Mathieu; Brown, Alastair J. H.; Kean, James; Errey, James C.; Robertson, Nathan J.; Fiez-Vandal, Cé dric; Andrews, Stephen P.; Congreve, Miles; Bortolato, Andrea; Mason, Jonathan S.; Baig, Asma H.; Teobald, Iryna; Doré , Andrew S.; Weir, Malcolm; Cooke, Robert M.; Marshall, Fiona H.; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7 3AX, UK; Heptares Therapeutics Ltd, BioPark, Broadwater Road, Welwyn Garden City, Hertfordshire AL7; (Nature, v.546, 2017, pp.254-258)
  • 40
    IL23R Variation Determines Susceptibility But Not Disease Phenotype in Inflammatory Bowel Disease
    Tremelling, Mark; Cummings, Fraser; Fisher, Sheila A.; Mansfield, John; Gwilliam, Rhian; Keniry, Andrew; Nimmo, Elaine R.; Drummond, Hazel; Onnie, Clive M.; Prescott, Natalie J.; Sanderson, Jeremy; Bredin, Francesca; Berzuini, Carlo; Forbes, Alastair; Lewis, Cathryn M.; Cardon, Lon; Deloukas, Panos; Jewell, Derek; Mathew, Christopher G.; Parkes, Miles; Satsangi, Jack; IBD Research Group, Addenbrooke’s Hospital, University of Cambridge, Cambridge, England; Gastroenterology Unit, Radcliffe Infirmary, University of Oxford, Oxford, England; Division of Genetics and Molecular Medicine, Guy’s, King’s College and St Thomas’ School of Medicine, London, England; Faculty of Medical Sciences, University of Newcastle, Newcastle upon Tyne, England; Wellcome Trust Sanger Institute, Hinxton, Cambridge, England; Wellcome Trust Sanger Institute, Hinxton, Cambridge, England; Department of Gastroenterology, University of Edinburgh, and Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland; Department of Gastroenterology, University of Edinburgh, and Gastrointestinal Unit, Western General Hospital, Edinburgh, Scotland; Department of Medical and Molecular Genetics, King’s College London School of Medicine, Guy’s Hospital, London, United Kingdom; Department of Medical and Molecular Genetics, King’s College London School of Medicine,; (Gastroenterology, v.132, 2007, pp.1657-1664)
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