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Discovery of (<i>S</i>)-2-(1-(4-Amino-3-(3-fluoro-4-methoxyphenyl)-1<i>H</i>-pyrazolo[3,4-<i>d</i>]pyrimidin-1-yl)propyl)-3-cyclopropyl-5-fluoroquinazolin-4(3<i>H</i>)-one (IHMT-PI3Kδ-372) as a Potent and Selective PI3Kδ Inhibitor for the Treatment of Chronic Obstructive Pulmonary Disease
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Li, Feng;
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Wang, Li;
Liu, Jing;
Liu, Qingsong;
Anhui Province Key Laboratory of Medical Physics and Technology;
CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology;
Institute of Health and Medical Technology , Hefei Institutes of Physical Science, Chinese Academy of Sciences , Hefei , Anhui 230031 , P. R. China;
Anhui Province Key Laboratory of Medical Physics and Technology;
CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology;
Institute of Health and Medical Technology , Hefei Institutes of Physical Science, Chinese Academy of Sciences , Hefei , Anhui 230031 , P. R. China;
Anhui Province Key Laboratory of Medical Physics and Technology;
CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology;
Institute of Health and Medical Technology , Hefei Institutes of Physical Science, Chinese Academy of Sciences , Hefei , Anhui 230031 , P. R. China;
Anhui Province Key Laboratory of Medical;
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