검색어 : 통합검색[Symons Julian]
총 116건 중 116건 출력
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111
- Molecular Basis for the Selective Inhibition of Respiratory Syncytial Virus RNA Polymerase by 2'-Fluoro-4'-Chloromethyl-Cytidine Triphosphate
- Deval, Jerome; Hong, Jin; Wang, Guangyi; Taylor, Josh; Smith, Lucas K.; Fung, Amy; Stevens, Sarah K.; Liu, Hong; Jin, Zhinan; Dyatkina, Natalia; Prhavc, Marija; Stoycheva, Antitsa D.; Serebryany, Vladimir; Liu, Jyanwei; Smith, David B.; Tam, Yuen; Zhang, Qingling; Moore, Martin L.; Fearns, Rachel; Chanda, Sushmita M.; Blatt, Lawrence M.; Symons, Julian A.; Beigelman, Leo; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alios BioPharma, Inc., South San Francisco, California, United States of America; Alio; (PLoS pathogens, v.11, 2015, pp.e1004995)
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112
- An in vivo duck hepatitis B virus model recapitulates key aspects of nucleic acid polymer treatment outcomes in chronic hepatitis B patients
- Debing, Yannick; Vanrusselt, Hannah; Degrauwe, Lars; Silva de Oliveira, Daniel Apolô nio; Kariuki, Christopher Kinyanjui; Ebwanga, Ebanja Joseph; Bashir, Shahbaz; Merckx, Wouter; Thatikonda, Santhosh Kumar; Rajwanshi, Vivek; Gohil, Vikrant; Hong, Jin; Kum, Dieudonné Buh; Acosta Sanchez, Abel; Chanda, Sushmita; Blatt, Lawrence M.; Jekle, Andreas; Symons, Julian A.; Smith, David B.; Raboisson, Pierre; Lin, Tse-I; Beigelman, Leonid; Paeshuyse, Jan; ; (Antiviral research, v.224, 2024, pp.105835)
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113
- The Substitutions L50F, E166A, and L167F in SARS-CoV-2 3CLpro Are Selected by a Protease Inhibitor <i>In Vitro</i> and Confer Resistance To Nirmatrelvir
- Jochmans, Dirk; Liu, Cheng; Donckers, Kim; Stoycheva, Antitsa; Boland, Sandro; Stevens, Sarah K.; De Vita, Chloe; Vanmechelen, Bert; Maes, Piet; Trü eb, Bettina; Ebert, Nadine; Thiel, Volker; De Jonghe, Steven; Vangeel, Laura; Bardiot, Dorothé e; Jekle, Andreas; Blatt, Lawrence M.; Beigelman, Leonid; Symons, Julian A.; Raboisson, Pierre; Chaltin, Patrick; Marchand, Arnaud; Neyts, Johan; Deval, Jerome; Vandyck, Koen; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Virology & Chemotherapy, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Virology & Chemotherapy, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; CISTIM Leuven vzw, Leuven, Belgium; Aligos Therapeutics, Inc., South San Francisco, California, USA; Aligos Therapeutics, Inc., South San Francisco, California, USA; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Clinical & Epidemiological Virology, Leuven, Belgium; KU Leuven, Department of Microbiology, Immunology & Transplantation, Rega Institute, Laboratory of Clinical & Epidemiological Virology, Leuven, Belgium; Institute of Virology and Immunology, University of Bern, Bern, Switzerland; Institute of Virology and Imm; (mBio, v.14, 2023, pp.e02815-22)
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114
- The substitutions L50F, E166A and L167F in SARS-CoV-2 3CLpro are selected by a protease inhibitor <i>in vitro</i> and confer resistance to nirmatrelvir
- Jochmans Dirk; Liu Cheng; Donckers Kim; Stoycheva Antitsa; Boland Sandro; Stevens Sarah K; De Vita Chloe; Vanmechelen Bert; Maes Piet; Trüeb Bettina; Ebert Nadine; Thiel Volker; De Jonghe Steven; Vangeel Laura; Bardiot Dorothée; Jekle Andreas; Blatt Lawrence M; Beigelman Leonid; Symons Julian A; Raboisson Pierre; Chaltin Patrick; Marchand Arnaud; Neyts Johan; Deval Jerome; Vandyck Koen; ; (, v., 2022, )
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115
- Directed evolution of gene-shuffled IFN-α molecules with activity profiles tailored for treatment of chronic viral diseases
- Brideau-Andersen, Amy D.; Huang, Xiaojian; Sun, Siu-Chi Chang; Chen, Teddy T.; Stark, Diane; Sas, Ian J.; Zadik, Linda; Dawes, Glenn N.; Guptill, Douglas R.; McCord, Robert; Govindarajan, Sridhar; Roy, Ajoy; Yang, Shumin; Gao, Judy; Chen, Yong Hong; Skartved, Niels Jørgen Ø.; Pedersen, Annette K.; Lin, David; Locher, Christopher P.; Rebbapragada, Indrani; Jensen, Anne Dam; Bass, Steven H.; Nissen, Torben L. Straight; Viswanathan, Sridhar; Foster, Graham R.; Symons, Julian A.; Patten, Phillip A.; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxygen, Incorporated, 515 Galveston Drive, Redwood City, CA 94063; ; *Maxyg; (Proceedings of the National Academy of Sciences of the United States of America, v.104, 2007, pp.8269-8274)
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116
- The Discovery and Preclinical Profile of ALG-000184, a Prodrug of the Potent Hepatitis B Virus Capsid Assembly Modulator ALG-001075
- Vendeville, Sandrine; Amblard, Franck; Bassit, Leda; Beigelman, Leonid N.; Blatt, Lawrence M.; Chen, Xiaoyuan; Chou, Lang; Kum, Dieudonné Buh; Chanda, Sushmita; Deval, Jerome; Geng, Xiu; Gupta, Kusum; Jekle, Andreas; Hu, Haiyang; Hu, Xiaojuan; Kang, Hyunsoon; Liu, Cheng; Liu, Jyanwei; McGowan, David C.; Misner, Dinah L.; Raboisson, Pierre; Sanchez, Abel Acosta; Serebryany, Vladimir; Stoycheva, Antitsa D.; Symons, Julian A.; Tan, Hua; Vanrusselt, Hannah; Williams, Caroline; Welch, Michael; Zhang, Liangliang; Zhang, Qingling; Zhang, Yafeng; Schinazi, Raymond F.; Smith, David B.; Debing, Yannick; Aligos Belgium BV , Gaston Geenslaan 1 , 3001 Leuven , Belgium; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics , Emory University School of Medicine and Children’s Healthcare of Atlanta , 100 Woodruff Circle , Atlanta , Georgia 30322 , United States; Center for ViroScience and Cure, Laboratory of Biochemical Pharmacology, Department of Pediatrics , Emory University School of Medicine and Children’s Healthcare of Atlanta , 100 Woodruff Circle , Atlanta , Georgia 30322 , United States; Aligos Therapeutics, Inc. , 1 Corporate Dr., Second Floor , South San Francisco , California 94080 , United States; Aligos Therapeutics, Inc. , 1 Corporate Dr., Second Floor , South San Francisco , California 94080 , United States; WuXi AppTec , 288 Fute Zhong Road Waigaoqiao Free Trade; (Journal of medicinal chemistry, v.67, 2024, pp.21126-21142)
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